Breast cancer is the cancer with the highest incidence in Taiwanese women, and there is a trend of younger age in recent years. Physician Tseng Yandun from the General Surgery Department of Kaohsiung Veterans General Hospital said that when a physician diagnoses breast cancer, the tumor size, lymph nodes, and distant metastases are evaluated for staging. In addition, it can also distinguish subtypes according to the expression of breast cancer genes, and determine whether the patient belongs to luminal A type, luminal B type, HER-2 positive type, or the so-called triple negative type, so as to choose different treatment combinations.
Must understand! Breast Cancer telemarketing list Treatment Key Report Dr. Zeng Yandun explained that breast cancer subtypes are mainly judged by ER (estrogen receptor), PR (progesterone receptor), HER2 (human epidermal growth factor receptor), and Ki-67 (cancer growth index). ER and PR are hormone receptors. If breast cancer cells have hormone receptors, they will be stimulated by hormones to grow. HER-2 is the human epidermal growth factor receptor. When HER-2 is overactivated, breast cancer cells will accelerate the growth and metastasis. Ki-67 is an index used to assess cancer growth, because Ki-67 is a protein associated with cell division and growth, and the faster the cell divides, the higher the expression of Ki-67.
Breast cancer subtypes based on gene expression: Luminal type A: ER positive, and/or PR positive, HER2 negative, low Ki-67. Lumen type B1: ER positive, and/or PR positive, HER2 negative, high Ki-67. Lumen type B2: ER positive, and/or PR positive, HER2 positive. HER-2 positive type: ER negative, PR negative, HER2 positive. Triple negative: ER negative, PR negative, HER2 negative. 02 In the face of breast cancer, don't give up treatment for financial pressure-Complete-02 Photo Credit: Care Online Physicians distinguish between breast cancer subtypes because the prognosis and treatment strategies of these subtypes are different. arrow_forward_iosunderstand more Powered by GliaStudio.